ncRNA name | LINC00152 |
ncRNA Category | lncRNA |
ID | 112597 |
Ensembl | ENSG00000222041 |
Synonyms | CYTOR; C2orf59; NCRNA00152 |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples, normal retinas; RB cell lines Y79 and SO-RB50; RPE cell line ARPE-19 |
Methods | transfection, qRT-PCR, CCK-8 assay, colony formation assay, apoptosis assay, wound healing assay, Western blot, xenograft |
Expression pattern | up-regulated |
Functional description | Knockdown of LINC00152 significantly inhibited cell proliferation, colony formation, migration, and invasion and promoted cell apoptosis and caspase-3 and caspase-8 activities in vitro, as well as suppressing tumorigenesis in vivo. |
PubMed ID | 29922070 |
Year | 2018 |
Title | Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression. |
Drug-related ncRNA | NO |
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