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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name LINC00152
ncRNA Category lncRNA
ID 112597
Ensembl ENSG00000222041
Synonyms CYTOR; C2orf59; NCRNA00152
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retinas; RB cell lines Y79 and SO-RB50; RPE cell line ARPE-19
Methods transfection, qRT-PCR, CCK-8 assay, colony formation assay, apoptosis assay, wound healing assay, Western blot, xenograft
Expression pattern up-regulated
Functional description Knockdown of LINC00152 significantly inhibited cell proliferation, colony formation, migration, and invasion and promoted cell apoptosis and caspase-3 and caspase-8 activities in vitro, as well as suppressing tumorigenesis in vivo.
PubMed ID 29922070
Year 2018
Title Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression.
Drug-related ncRNA NO

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